|
KMID : 1161420110140090939
|
|
Journal of Medicinal Food
2011 Volume.14 No. 9 p.939 ~ p.943
|
|
|
Bioactive Properties of Tynanthus panurensis (Bureau) Sanwith Bark Extract, the Amazonian “Clavo Huasca”
|
|
Morales Lidia
Acero Nuria
Galan Antonio
Perez-Garcia Carmen
Alguacil Luis Fernando
Munoz-Mingarro Dolores
|
|
|
Abstract
|
|
|
|
Tynanthus panurensis (Bureau) Sanwith (Bignoniaceae) is a liana vine used in traditional Amazonian medicine as a tonic and energizer as well as a treatment for rheumatism. These traditional indications prompted this study of the antioxidant and anti-inflammatory activities of T. panurensis bark extract (ETP). Phytochemical analysis of ETP showed the presence of saponins and a high concentration of phenols and flavonoids. A battery of in vitro tests revealed that the extract has free radical?scavenging antioxidant properties and reduces microsomal lipid peroxidation, uric acid synthesis, and tumor necrosis factor-α production. The anti-inflammatory properties of ETP were further confirmed in vivo in a rat carrageenan edema model, in which the extract exhibited a potent activity. These results support the idea that T. panurensis bark extract could be beneficial for treating inflammation and are in agreement with one of the main traditional uses of this plant.
|
|
|
KEYWORD
|
|
|
antioxidant, Bignoniaceae, carrageenan edema, lipid peroxidation, radical scavenger
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|